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The William Gowers Clinical Research Fellowships

The Epilepsy Foundation's William Gowers Clinical Research Fellowships have been supported by grants from Abbott Laboratories since 1986. The Gowers Fellowship is awarded annually to a physician/scientist who is embarking on a career in academic clinical medicine and who wishes to undertake a specific project in epilepsy research.

Fellowship applications compete on the basis of scientific merit; in each case a senior academic clinician serves as a preceptor to the successful recipient. For the past eighteen years, these fellowships have attracted outstanding young people to the field of research while providing them with a priceless opportunity to learn—and contribute to—the latest developments in patient care.

The Gowers fellows continue to be active in the field of epilepsy research and clinical care. They publish, they teach, they treat, and they are rising to leadership positions in their profession. The Epilepsy Foundation and Abbott Laboratories are proud of the achievements of the Gowers fellows, and look forward to their future contributions to the understanding of epilepsy, its successful treatment, and ultimate cure.

About William R. Gowers (1845-1915)

The William Gowers Clinical Research Fellowships are named in honor of William R. Gowers, a British physician who was one of a small group of brilliant neurologists who, towards the end of the nineteenth century, led the way to a new understanding of the brain and epilepsy. His book, Epilepsy and Other Chronic Convulsive Diseases, published in 1881, and his subsequent lectures and writings, are generally cited as marking the beginning of modern concepts of epilepsy, its causes, symptoms and treatment.

In addition to teaching and writing, Gowers spent most of his professional life treating patients in London's National Hospital for the Paralyzed and Epileptic (now the National Hospital, Queens Square). He was a clinician, a physician-scientist, a man whose careful observations, supported by data, and principles of patient care and management exemplify the characteristics which the Epilepsy Foundation and Abbott Laboratories hope to cultivate in the recipients of the William Gowers Clinical Research Fellowships.

The William R. Gowers Clinical Research Fellows: 1986—2006

2006

Adam Olding Hebb, M.D.
University of Minnesota
"Hyperspectral Optical Imaging of Language Processing in the Epilepsy Population"
Jeffery Ojemann, M.D. (Preceptor)

2005

William Stanley Anderson, M.D., Ph.D.
Johns Hopkins University School of Medicine
"Studies of Stimulus parameters for Seizure Disruption using Neural Network Siulations"
Gregory Kent Bergey, M.D. (Preceptor)

2004

Lawrence W. Ver Hoef, M.D.
University of Alabama at Birmingham
"Left Mesial Temporal Sclerosis and Verbal Memory: A Magnetoencephalography Study"
Robert C. Knowlton, M.D. (Preceptor)

2003

Jack J. Lin, M.D.
University of California, Los Angeles
"Extrahippocampal Structural Abnormalities in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis"
Jerome Engel, Jr. M.D., Ph.D. (Preceptor)

2002

Kathryn McVicar, M.D.
Montefiore Medical Center
"Epileptic EEG Abnormalities and Immunologic Function in Children with Regression of Language or Cognition"
Shlomo Shinnar, M.D., Ph.D. (Preceptor)

2001

Heidi Majors, M.D.
The Johns Hopkins University
"Functional Mapping of Sensorimotor and Language Cortices in Patients with Epilepsy Using Electrocorticographic Frequency Analysis: A Comparison with Cortical Electrical Stimulation"
Nathan E. Crone, M.D. (Preceptor)

2000

Lori Uber-Zak, D.O.
Barrow Neurological Institute
"Salivary AED Levels at the Time of a Breakthrough Seizure"
David Blum, M.D. (Preceptor)

1999

Barbara C. Jobst, M.D.
Dartmouth-Hitchcock Medical Center
"Electroclinical Findings in Secondarily Generalized Seizures"
Peter D. Williamson, M.D. (Preceptor)

1998

Jehuda Sepkuty, M.D.
The Johns Hopkins University
"Glutamate Transporter EAAC1 and Chronic Epilepsy"
Jeffrey D. Rothstein, M.D. (Preceptor)

1997

Scott J. Sherman, M.D., Ph.D.
University of Arizona
"Modulation of Potassium Channel Inactiviation by Antisense Knockdown of the Beta-1 Subunit: A Potential Therapy for Focal Epilepsies"
David M. Labiner, M.D. (Preceptor)

1996

Thomas Perkins, M.D., Ph.D.
Duke University Medical Center
"Expression of GABAA Receptor Subunit mRNAs in Hippocampi from Patients with Complex Partial Epilepsy"
David A. Hosford, M.D., Ph.D. (Preceptor)

1995

Donald Born, M.D., Ph.D.
University of Washington
"Neurotrophins and Epileptogenesis"
Philip A. Schwartzkroin, Ph.D. (Preceptor)

1994

Fu Du, Ph.D.
University of Maryland at Baltimore
"Selective Lesions of Layer III Neurons in Entorhinal Cortex: A Novel Model of Temporal Lobe Epilepsy"

1993

Kris Smith, M.D.
Barrow Neurological Institute/St. Joseph's Hospital
"Cholesterol Synthesis Inhibitor Model of Absence Epilepsy"
Robert S. Fisher, M.D., Ph.D. (Preceptor)

1992

Brian Litt, M.D.
Johns Hopkins Hospital
"A Neural Network-Based System for Automated Spike Detection"
Ronald P. Lesser, M.D. (Preceptor)

1991

Jane G. Boggs, M.D.
Medical College of Virginia
"Electrophysiologic Risk Factors in the Mortality of Status Epilepticus"
Robert J. DeLorenzo, M.D., Ph.D., M.P.H. (Preceptor)

1990

Amiram Katz, M.D.
Yale University School of Medicine
"Spatial and Temporal Analysis of Interictal Spikes, Electrographic and Clinical Seizures in Patients with Intractable Epilepsy"
Susan S. Spencer, M.D. (Preceptor)

1989

Martha J. Morrell, M.D.
Graduate Hospital, Philadelphia
"Psychophysiological Evaluation of Reproductive Behavior and Measurement of Reproductive Hormones in Epilepsy of Temporal Lobe Origin"
Marc Dichter, M.D., Ph.D., and Michael Sperling, M.D. (Preceptors)

1988

Peter Wade, M.D.
Yale University
"The Effects of Anti-Epileptic Drugs and Sleep on the Propagation of Epileptic EEG Spikes in Cortex"
John S. Ebersole, M.D. (Preceptor)

1987

Cynthia A. Rask, M.D.
University of Minnesota Comprehensive Epilepsy Program
"Catamenial Epilepsy"
Ilo E. Leppik, M.D. (Preceptor)

1986

Christopher M. De Giorgio, M.D.
University of California Los Angeles School of Medicine
"The Effects of Carbamazepine on Phenytoin Kinetics Examined by Stable Isotopes"
David M. Treiman, M.D. (Preceptor)

From the Fellows

"Without the Foundation's support, this research would not have been possible. [I] was able to acquire additional skills and knowledge regarding intracranial EEG recordings and presurgical diagnostic work-up for epilepsy surgery."
Barbara C. Jobst, M.D.

"Fellowship support from the Epilepsy Foundation in the form of the William Gowers Fellowship was crucial in my transition to an academic position."
Donald Born, Ph.D., M.D.

"I credit my work as a William Gowers fellow as a seminal influence on my career in epilepsy and neurophysiology …"
Jane G. Boggs, M.D.

"The preliminary data gathered during the fellowship was directly responsible for receiving an award from the NINDS. I am now in the process of completing these studies and will be publishing results shortly."
Scott J. Sherman, M.D., Ph.D.

"This fellowship was crucial to my research in status epilepticus and was key to my career!"
Christopher Michael De Giorgio, M.D.

"Funding by Abbott Laboratories and the Epilepsy Foundation is an important factor in helping new researchers, as myself, at the beginning of their career."
Jehuda Sepkuty, M.D.

"The Gowers Fellowship allowed me to undertake research on salivary antiepileptic drug levels in breakthrough seizures and obtain important training needed to advance my career."
Lori Uber-Zak, D.O.

"The Gowers Fellowship is allowing me to participate in the development of a novel presurgical mapping technique…"
Heidi Majors, M.D.

"The Gowers Fellowship has allowed me to explore the relationship between epilepsy and childhood language disorders…"
Kathryn McVicar, M.D.

"I believe that this project will be the beginning of a rewarding career in academic neurology in which I can use advanced brain mapping technology to discover biological mechanisms underlying neurobehavioral aspects of epilepsy."
Jack J. Lin, M.D.

"My study will examine verbal memory in patients with left mesial temporal lobe epilepsy."
Lawrence W. Ver Hoef, M.D.

For information on how to apply for the William Gowers Clinical Research Fellowships, contact:

Research Administration, Epilepsy Foundation
8301 Professional Place
Landover, MD 20785
(301) 459-3700
http://www.epilepsyfoundation.org